منابع مشابه
Experimental Chemotherapy
the heart of all pharmacological inquiry and the hope of chemotherapy. According to Lasagna, although drug effects are generally viewed as an inevitable sequence of phenomena induced by a stimulus, i.e., by an active chemical, pharmacological variables such as route and dose are insufficiently specified and the problems of the personality, attitudes of subjects and experimenters, or the charact...
متن کاملCompliance with the mass chemotherapy program for lymphatic filariasis.
OBJECTIVE To evaluate compliance with the single dose mass chemotherapy program for control of filariasis, and to determine factors influencing compliance in the Gampaha district. DESIGN A prospective study employing a pre-tested self-administered questionnaire. METHODS Four groups comprising individuals over one year old with residence in the Gampaha district for over one year were surveye...
متن کاملExperimental study: experimental evaluation of phospholipid system containing doxorubicin HCL for use in chemotherapy
Introdution: Common cancer treatment methods have many side effects. Therefore, the use of new methods for drug delivery to cancer cells is necessary. In the present study, nano formulations of lipid carriers containing doxorubicin have been synthesized and its physicochemical properties have been investigated. Methods: The present study was an experimental study. The liposomal systems were sy...
متن کاملChemotherapy in Experimental Cancer
Chemical agents being tested for their action on tumor growth are usually injected into animals with the hope that they will have a specific action on the malignant cell. While some chemicals have produced necrosis and regression of tumors, the effects often appear to be due to ischemia and cellular starvation resulting from vascular injury and thrombosis, rather than to a selective action of t...
متن کاملChemotherapy of Experimental Streptococcal Endocarditis
A B S T R A C T The ability of antibiotics to prevent Streptococcus sangutis endocarditis was tested in rabbits. Only vancomycin or a combination of penicillin G plus streptomycin always prevented infection when administered as a single dose. A loading dose of 30 mg/kg of phenoxymethyl penicillin (penicillin V) followed by additional 7.5 mg/kg doses for 48 h proved to be the only successful pro...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1950
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1950.tb01011.x